FISCHERLAB DUCOM Spinal Cord Research Center

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Itzhak Fischer, Ph.D. | Birgit Neuhuber, Ph.D.
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Publications

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Neural Stem Cells

Lepore AC, Walczak P, Rao MS, Fischer I, Bulte JWM. MR imaging of lineage-restricted neural precursors following transplantation into the adult spinal cord. Exp. Neurol. 2006 201(1):49-59. abstract

Lepore AC, Neuhuber B, Connors TM, Han SS, Liu Y, Daniels MP, Rao MS, Fischer I. Long-term fate of neural precursor cells following transplantation into developing and adult CNS.  Neuroscience. 2006:139(2):513-30 abstract PDF

Lepore A, Bakshi A, Swanger SA, Rao MS, Fischer I. Neural precursor cells can be delivered into the injured cervical spinal cord by intrathecal injection at the lumbar cord. Brain Research 2005:1045:206-216. abstract PDF

Lepore A, Fischer I. Lineage-restricted neural precursors survive, migrate and differentiate following transplantation into the injured adult spinal cord. Experimental Neurology 2005:194:230-242. abstract PDF

Li P, Tessler A, Han SSW, Fischer I, Rao MS, Selzer M. Fate of immortalized human neuronal progenitor cells transplanted into rat spinal cord. Arch Neurol. 2005:62(2):223-9. abstract PDF

Mitsui, T, Shumsky JS, Lepore A, Murray M, Fischer I. Transplantation of neuronal and glial restricted precursors into contused spinal cord improves bladder and motor functions, decreases thermal hypersensitivity, and modifies intraspinal circuitry. J. Neuroscience 2005:25(42):9624-36. abstract PDF

Bakshi A, Hunter C, Swanger S, Lepore A, Fischer I. Minimally invasive delivery of stem cells for spinal cord injury: advantages of the lumbar puncture technique. J. Neurosurgery Spine 2004:3:330-337. abstract PDF

Han SS, Liu Y, Tyler-Polsz C, Rao MS, Fischer I. Transplantation of glial-restricted precursor cells into the adult spinal cord:  Survival, glial-specific differentiation, and preferential migration in white matter. Glia 2004:45:1-16. abstract PDF

Lepore AC, Han SSW, Tyler-Polsz CJ, Cai J, Rao MS, Fischer I. Differential fate of multipotent and lineage-restricted neural precursors following transplantation into the adult CNS. Neuron Glia Biology 2004:1:113-126. abstract PDF

Liu Y, Han SSW, Wu Y, Tuohy TMF, Xue H, Cai J, Back SA, Sherman LS, Fischer I, Rao MS. CD44 expression identifies astrocyte-restricted precursor cells. Develop. Biol. 2004:276:31-46. abstract PDF

Han SS, Kang DY, Mujtaba T, Rao MS, Fischer I. Grafted lineage-restricted precursors differentiate exclusively into neurons in the adult spinal cord. Exp Neurol 2002:177:360-375. abstract PDF

Mujtaba T, Han SS, Fischer I, Sandgren EP and Rao MS.  Stable expression of the alkaline phosphatase marker gene by neural cells in culture and after transplantation into the CNS using cells derived from a transgenic rat. Exp. Neurol. 2002:174:48-57. abstract PDF

Wu YY, Mujtaba T, Han SSW, Fischer I and Rao MS. Isolation of a glial-restricted tripotential cell line from embryonic spinal cord cultures. Glia 2002:38:65-79. abstract PDF

Hormigo A, McCarthy M, Nothias JM, Hasegawa K, Huang W, Friendlander DR, Fischer I, Fishell G,  Grumet M. Radial glial cell line C6-R integrates preferentially in adult white matter and facilitates migration of co-implanted neurons in vivo. Exp. Neurol. 2001:168:310-322. abstract PDF

Chow SY, Moul J, Tobias C, Himes BT, Liu Y, Obrocka M, Hodge L, Tessler A, Fischer I. Characterization and intraspinal grafting of EGF/bFGF-dependent neurospheres derived from embryonic rat spinal cord. Brain Res. 2000:874:87-106. abstract PDF

Han S, Fischer I.Neural stem cells and gene therapy: Prospects for repairing the injured spinal cord. JAMA 2000:293:2300-2301. abstract PDF

Liu Y, Himes T, Solowska-Baird J, Moul J, Chow S, Tessler A, Snyder E, and Fischer I. Intraspinal delivery of neurotrophin-3 using neural stem cells genetically modified by recombinant retrovirus. Experimental Neurology.1999:158:9-26. abstract PDF

Lepore AC, and Fischer I. Phenotypic fate of lineage-restricted neural precursors following transplantation into the injured adult spinal cord. Exp. Neurol. (in press).

Boyne LJ, Fischer I, Shea TB. Role of vimentin in early stages of neuritogenesis in cultured hippocampal neurons. Int J Dev Neurosci. 1996 Oct;14(6):739-48.

Emery DL, Raghupathi R, Saatman KE, Fischer I, Grady MS, McIntosh TK. Bilateral growth-related protein expression suggests a transient increase in regenerative potential following brain trauma.  J Comp Neurol. 2000 Aug 28;424(3):521-31.

 

 

 

 

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