Biography

Dr. Waterhouse holds a B.S. degree in Biology from Muhlenberg College, Allentown, Pennsylvania and a PhD in Pharmacology from Temple University School of Medicine, Philadelphia. He has been at Drexel University College of Medicine (formerly Hahnemann University; MCP-Hahnemann University) since 1986 where he is now a tenured Professor of Neurobiology and Anatomy. He was initially recruited to the Department of Physiology and Biophysics, Hahnemann University School of Medicine, Philadelphia, PA as an Associate Professor and to assist in the development of a neuroscience research program at the university. In 1988 he developed and was subsequently appointed Director of the university's first Neuroscience Graduate Program; a post he held until 1994. In 1992 he was promoted to Professor of Physiology and Biophysics with tenure. In 1994 Hahnemann University merged with the Medical College of Pennsylvania and Dr. Waterhouse was invited to join the Department of Neurobiology and Anatomy in the newly formed medical school. He continued in his role as Director of the Neuroscience Graduate Program at MCP-Hahnemann (now Drexel University College of Medicine) until 2001 when he was appointed Associate Dean of Biomedical Graduate Studies in the College of Medicine - Drexel University (2001-06) and, later, Vice-Dean of Biomedical Graduate and Postgraduate Studies (2006-14), and most recently Vice Dean of the Graduate School of Biomedical Sciences and Professional Studies, and Interim Director, Division of Biomedical Science Programs (2014-15). His primary research interest is the neurobiology of central monoaminergic systems, norepinephrine and serotonin, and the actions of psychostimulant drugs. His laboratory has been continuously funded by federal (NIH) and private agencies since 1980. He has used a combination of electrophysiological (anesthetized and waking animals), neuroanatomical, behavioral and molecular profiling techniques to characterize the fundamental neurobiology of these two monoamine transmitter systems. Dr. Waterhouse is best known for demonstrating the ability of norepinephrine and serotonin to modulate the responsiveness of single neurons and ensembles of single neurons to synaptic inputs thereby altering the signal processing capabilities of the sensory, motor and cognitive circuitries. His laboratory has also identified important neurochemical and topographic organizational features of these two monoamine pathways. Most recently, he and his colleagues have been using multi-neuron recording strategies in waking animals to evaluate the impact of psychostimulant drugs on the signal processing capabilities of cells and circuits along sensory pathways and in prefrontal cortex decision-making networks. Overall, his work has contributed significantly to our understanding of the role of noradrenergic and serotonergic systems in sleep-waking, arousal, and attention; as well as mechanisms underlying stress/anxiety, depression, psychostimulant drug abuse and ADHD. To his credit are more than 100 publications in refereed journals, over 145 abstracts, 11 book chapters, and one monograph. He has served as primary mentor for 17 postdoctoral fellows and 30 graduate students and is currently Senior Associate Editor for the journal Brain Research and a reviewer for the Biobehavioral Regulation, Learning and Ethology Study Section of NIH. Among numerous awards are a NIH Research Career Development Award 1987-92 and the Esther A. and Joseph Klingenstein Fellowship Award in the Neurosciences in 1983. He was elected as a member of the American College of Neuropsychopharmacology in 1996 and promoted to fellow in 2014.