Paraventricular Thalamus

The paraventricular nucleus of the thalamus (PVT) functions as a major node in the limbic system, connecting homeostatic forces of the hypothalamus that act to maintain energy levels with non-homeostatic forces of other limbic nuclei that promote reward-seeking.

Our laboratory is currently investigating how subregions of the PVT communicate with other limbic brain regions to play distinct roles in alcohol and sucrose intake.

Alcohol drinking causes orexin from the hypothalamus to stimulate neurons in the anterior PVT.